The Southernmost House is an adults only property. All guests must be 18 years of age or older.
Enjoy Your Next Getaway in Elegance
Relax, Unwind, & Escape
Surround yourself in upscale elegance at the magnificent Southernmost House.
When you take a dip in the zero-entry heated pool that is perched directly on the oceanfront, it feels like the crystal-clear waters ebb and flow into the horizon. Find out why our famous bed and breakfast has been the Key West, Florida boutique hotel of choice for Presidents, royalty, and famous figures like Ernest Hemingway.
Relax, unwind, and escape from everyday life on the quieter end of Duval Street in a gorgeous setting that stretches out around our charming, restored Victorian house.
Rated #7 of 51 Hotels in Key West
"Our week long stay was perfect... it was paradise from the beautiful setting (pool, bar and porch overlooking the ocean) to iguanas, pelicans and a rabbit... the historic house was intriguing... the location was exactly what we were looking for, quiet for relaxing but close to wonderful restaurants and attractions... the owner, often present on the site, was informative and helpful... the staff were friendly, pleasant and accommodating... many random acts of kindness... the weather was perfect too... only problem was that we had to return home to winter but we already made our reservation for January 2019!"
Feel the Stress Melt Away
Melt away the stress by staying in one of our elegantly-appointed, amenity-rich guestrooms, spacious suites, our ultra elegant Lopez House.
Start each day with a continental breakfast, a sweet and savory spread of your favorite foods, stay connected with Wi-Fi access, swing in a hammock facing the sea, and enjoy personal concierge service from our friendly and attentive staff. Our tropical setting is also the perfect backdrop for your honeymoon, or special event.