A Historic Beachfront Key West Boutique Hotel

All guest must be 18 years of age or older due to the museum and historic pieces within the Southernmost House Hotel.
Plan your vacation in paradise at one of the most historic Key West Beach hotels, and surround yourself in upscale elegance at the magnificent Southernmost House. When you take a dip in the zero-entry heated pool that is perched directly on the oceanfront, it feels like the crystal-clear waters ebb and flow into the horizon. Find out why our famous bed and breakfast has been the Key West, Florida boutique hotel of choice for Presidents, royalty, and famous figures like Ernest Hemingway. Relax, unwind, and escape from everyday life on the quieter end of Duval Street in a gorgeous setting that stretches out around our charming, restored Victorian house.
Melt away the stress by staying in one of our elegantly-appointed, amenity-rich guestrooms, spacious suites, our ultra elegant Lopez House. Start each day with a continental breakfast, a sweet and savory spread of your favorite foods, stay connected with Wi-Fi access, swing in a hammock facing the sea, and enjoy personal concierge service from our friendly and attentive staff. Our tropical setting is also the perfect backdrop for your dream wedding, honeymoon, or special event.